Research Interests

Associate Professor Julian Trollor

(Position Details)
Phone 02 99319160
Email
Qualifications MB BS Hons UNSW, MD, FRANZCP
 
School/Unit
School of Psychiatry
http://psych.med.unsw.edu.au/
 
Broad Research Areas
Ageing
Imaging / Radiology
Inflammation
Genetics - Genome Analysis
Psychiatry
 
Specific Research Keywords
Intellectual disability
Imaging
Learning disorders
Developmental Neuroscience
Developmental disability
 
Research Interests

Research projects are available to suit a variety of students at the ILP, Honours, Masters and PhD level. There are 3 broad streams to my current research: 1. Brain Ageing: determinants and correlates of brain ageing with a focus on brain imaging, metabolic, cardiovascular and inflammatory factors, nutrition, and gene-environment inteactions. Study data is derived from two large ageing gohorts, the Sydney Memory and Ageing Study and the Older australian Twins Study. 2. Developmental Disability Neuropsychiatry: a number of focus areas including ageing and dementia in intellecutally disabled adults, intellecual disability mental health within the criminal justice system, human rights issues in health care of intellecually disabled adults. 3. Other Neuropsychaitric Disorders: I have an established interest in a variety of neuropsychaitric conditions including the neuropsychiatry of epilepsy, adult ADHD, novel treatments for depression (including VNS)and drug induced movement disorders including NMS.
 
ILP Research Interests (Will supervise ILP students)
Ageing
Cognition
Dementia
Inflammation
Intellectual Disabilities
 
Project Topics for current Honours Students
1. microbleeds and cognition in elderly individuals.
 
Teaching Interests
Undergraduate teaching interests: lectures and tutorials for medical students integrating neurosciences and clinical material. Postgraduate teaching for psychiatry trainees focuses assessment and management of Intellectual Disability Mental Health and other Neuropsychiatric disorders.
 
Society Memberships & Professional Activities
Current Secretary & Treasurer, International Neuropsychiatric Association
Current member, Neuropsychiatric Commission of the International League Against Epilepsy (ILAE)
Member, Reviewable Disability Deaths Committee of the NSW Ombudsman
Fellow, Royal Australian and New Zealand College of Psychiatrists (RANZCP)
Secretary, Neuropsychiatry Section of RANZCP
Member, Faculty of Psychiatry of Old Age
Member, Australasian Society for Psychiatric Research
Founding Member and Co-Convenor, Neuropsychiatry Interest Group
Member, Movement Disorder Society
Member, Australian Medical Association
Professional Member, Huntington's Disease Association
Registered Medical Practitioner, Medical Board of NSW
Member, Australian Salaried Medical Officers Association
Member, Christianity and Psychiatry Group
Invited reviewer for a number of national and international medical/neuroscience journals
 
Funding Sources
NHMRC 2003 Equipment Grant ID No. 219355 to establish a basic research EEG/ERP Laboratory integrated with a Cognitive Testing Laboratory. $41,036 (Sachdev, Mitchell, Trollor, Breakspear, Malhi, Loo)

Faculty Research Grant 2005, University of New South Wales $20,000. This money was used to establish a pilot for the NSW Twin Study of Brain ageing and Cognition.

NHMRC/ARC Ageing Well Ageing Productively Grant 401162, $2.0M for 2007-2011; Gene-Environment interactions in healthy brain ageing and age-related neurodegeneration “Older Australian Twins Study/OATS” (Sachdev P, Martin N, Ames D, Schofield P, Broe T, Brodaty H, Trollor J, Wright M, Wen W, Halliday G, Lee T)

NHMRC Project Grant ID 510175, $560,750 for 2008-2010 Early detection of MCI and dementia using multidimensional analysis of structural MRI by computational methods (Wen W, Trollor J, Ratnanather J, Wang L, Beg M)

NHMRC Dementia Research Grant Project ID: 510124; 2008-2010; $AU904,409 for 2008-2010. The role of metabolic and inflammatory factors in cognitive decline and cerebrovascular pathology in the elderly (Trollor J, Campbell L, Samaras K, Brodaty H, Wright M, Martin N, Wen W, Baune B)
 
Other Postgraduate Research

1. Masters Project examining the relationship between motor slowing and cognition in late life
 
Key works/Publications
Recent Submissions
Slavin M, Brodaty H, Kochan NA, Crawford J, Trollor J, Draper B, Sachdev P. Prevalence and Predictors of Subjective Cognitive Complaints in the Sydney Memory and Ageing Study. Submitted to American Journal of Geriatric Psychiatry.

Kochan NA, Slavin M, Brodaty H, Crawford J, Trollor J, Draper B, Sachdev P. Impact of different neuropsychological methods on prevalence of ‘objective’ mild cognitive impairment in a community setting. Submitted to American Journal of Geriatric Psychiatry.

Thompson C, Brodaty H, Trollor J, Sachdev P. Behavioural and psychological symptoms associated with dementia subtype and severity. Submitted to International Psychogeriatrics.

Jayasena T, Poljak A, Smythe G, Raftery M, Hill M, Brodaty H, Trollor J, Kochan N, Sachdev P. Involvement of acute phase proteins in Mild Cognitive Impairment and Alzheimer’s disease. Submitted to Journal of Alzheimer’s Disease.

Sachdev P, Lammel A, Trollor J, Lee T, Wright M, Ames D, Wen W, Martin N, Brodaty H, Schofield P. A comprehensive neuropsychiatric study of elderly twins: The Older Australian Twins Study. Accepted by Twins Research and Human Genetics Journal

Loy C, Krill J, Trollor J, Kiernan M, Kwok J, Vicic S, Halliday G, Hodges J. A 48 year old woman with complex delusions. Accepted by Nature Reviews Neurology 03/07/09 Manuscript # NRNEUROL-09-060V1

Valenzuela M, Kochan N, Sachdev P, Slavin M, Trollor J, McIntosh A, Breakspear M. Different Brain Networks Account for Efficiency & Variability of Spatial Working Memory following Inverse Demand-Dependent Quadratic Functions. Submitted to Journal of Neuroscience

Recent Publications
Trollor J, Chen X, Sachdev P. Neuroleptic Malignant Syndrome Associated With Atypical Antipsychotic Drugs. CNS Drugs 2009; 23(6):477-492.

Chua T, Wen W, Chen X, Kochan N, Slavin M, Trollor J, Brodaty H, Sachdev P. Diffusion Tensor Imaging of the Posterior Cingulate is a Useful Biomarker of Mild Cognitive Impairment. American Journal of Geriatric Psychiatry 2009;17 (7): 602-613.

Trollor J, Anderson T, Sachdev P, Brodaty H, Andrews G. Age Shall Not Weary Them: Mental Health in the Middle-aged and Elderly. Australian and New Zealand Journal of Psychiatry 2007; 41:581 – 589

Anderson T, Sachdev P, Brodaty H, Trollor J, Andrews G. Effects of sociodemographic and health variables on Mini-Mental State Examination (MMSE) scores in older Australians. Am J Geriatric Psychiatry 2007;15:467–476

Trollor J, Anderson T, Sachdev P, Brodaty H, Andrews G. Prevalence of Mental Disorders in the Elderly: The Australian National Mental Health and Well-being Survey. American Journal of Geriatric Psychiatry 2007; 15:455–466

Trollor J, Sachdev P, Haindl, W, Wen, W, Walker B. Combined Cerebral Blood Flow Effects of a Cholinergic Agonist (Milameline) and a Verbal Recognition Task in Early Alzheimer's Disease. Psychiatry and Clinical Neurosciences 2006; 60:616-625.

Trollor J, Sachdev P, Haindl, W, Wen, W, Walker B. A High-Resolution Single Photon Emission Computed Tomography Study of Verbal Episodic Memory in Alzheimer’s Disease. Dementia and Geriatric Cognitive Disorders 2006;21:267-274


Trollor J. Normal Pressure Hydrocephalus and Schizophrenia (Chapter) in Secondary Schizophrenia, Sachdev P, Keshavan M (eds). Cambridge University Press, Submitted.

Looi J, Trollor J, Sachdev P. The Neurological Aspects of Ageing. Chapter 13, pages 465-502 In Handbook of Clinical Neuroepidemiology V. Feigin, P. Bennett (ed) Novo Science Publishers, Inc, NY 2006. ISBN 1 60021 511 4
 
Further Information
http://psych.med.unsw.edu.au/psychweb.nsf/page/Brainage


Profile last updated: 16/10/2009

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Julian Trollor

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Ageing
Imaging / Radiology
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Genetics - Genome Analysis
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